Super Resolution Imaging System
Using appropriate dyes, the fluorescent signal decay can be combined with single molecule localization techniques to achieve 20 nm resolution.
The NanoAmaze super resolution (SR) imaging system achieves a 10-fold improvement compared to conventional confocal microscopy.
It allows nanoscale quantification of protein localization or protein-protein interaction.
The super resolution microscope can be used for biological research in cell biology, neuron biology, immunology, virology and nanomaterials.
Super resolution imaging is a combination of physics, chemistry, biology, computer science and engineering technology. This interdisciplinary nature can make it challenging for biologists (experimental design, sample preparation, equipment calibration, software configuration, data analysis). In collaboration with HKUST SRIC, NamoAmaze has built a team that provides customized hardware, software and comprehensive technical support. Ultimately our customers benefit when they get the best results with minimal effort.
Super Resolution Imaging Plan Exclusively For You
The intermediate image is split and imaged on EMCCD sensor through two separate optical paths simultaneously. Compared with general super resolution microscopy, long term acquisition of super resolution imaging benefits from the two channel design, which reduces photobleach and halves the imaging time.
Real-time locking system compensates lateral sample drift in caused by environmental conditions (temperature change, air flow, vibratior noises). Compared with post processing techniques used by others, the sample locking module designed by NBI can compensate this drift at nanometer resolution with high reliability.
ROHDEA provides improved user experience compared with competing imaging software solutions that are function-oriented and are harder to use. ROHDEA structures super resolution imaging workflow into four steps: 1. view preparing, 2. wide-field image acquisition, 3. super resolution image testing and 4. super resolution image acquisition. This standardized sequence of steps is easier to follow compared with traditional approaches.
Users can analyze the reconstructed super resolution images with SPRUCE, an image analysis tool also developed by NBI, to get customized analysis reports. Analysis of the result can provide useful information such as the distribution of cluster sizes/ patterns, localization distribution, error distribution etc.
Judging whether a new technology will be useful for a particular application requires experience. NBI can give you the answer rapidly, with our academic strengths and our knowledge base in the field. We also customize an imaging plan for your project. You can also choose our imaging service, with which you can test your hypothesis within weeks. Contact us now to discuss your imaging project!
Hardware after-sales service doesn't just mean hardware warranty -- helping you run your machine is also considered to be an important part of NBI service. Our consultation service includes trouble shooting, sharing technical experience, data analysis and modeling, statistical analysis, etc.
Following a standard "step-by-step" manual process can produce the optimal result for a demo sample. However your particular samples may require a different approach. NBI's scientists in different fields can provide professional training to the users, so they know which technique will work best for their situation.
Leading edge technologies can provide an advantage in research. In our long-term technical collaboration, our customers have priority access to our most advanced technologies. Furthermore, NBI also provides customized solutions for your research needs.